Estimated glomerular filtration rate and its association with sarcopenia in elderly people living in the community
DOI:
https://doi.org/10.12873/461jsantosKeywords:
Sarcopenia, Elderly, Chronic renal failureAbstract
Introduction: Factors such as chronic non-communicable diseases and sarcopenia are frequently associated with reduced estimated glomerular filtration rate (eGFR) and lower longevity in older adults. Objective: To evaluate the eGFR and its association with sarcopenia in community-dwelling elderly individuals. Methodology: This population-based cross-sectional study included 548 older adults (≥ 60 years) living in 11 municipalities in the State of Alagoas, Brazil. eGFR was calculated using the Chronic Kidney Disease Epidemiology Collaboration 2021 equation and classified according to kidney disease: Improving Global Outcomes 2024. Sarcopenia was defined based on the European Working Group on Sarcopenia in Older People 2019 criteria. Results: The mean age was 71.5 ± 28.6 years; 67.7% were women, 50.0% were overweight, 67.7% had hypertension, and 32.6% had diabetes. Reduced eGFR (<60 mL/min/1.73 m²) was observed in 19.5% of the sample. Probable sarcopenia was identified in 21.7%, with confirmed sarcopenia in 7.6%, but no association with eGFR was found. Age, sex, hypertension, number of medications, and waist circumference were significantly associated with reduced eGFR (p < 0.005). Conclusion: Sarcopenia was not directly associated with eGFR, although shared factors such as advanced age, hypertension, abdominal fat accumulation, and reduced muscle strength were observed. The characteristics of community-dwelling older adults may have influenced the absence of sarcopenia diagnosis. Nevertheless, the findings highlight relevant risk factors for chronic kidney disease in this population. Preventive strategies should prioritize individuals with abdominal obesity, hypertension, and women.
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