Variation in body weight and hemoglobin level in patients with tuberculosis treated at a public health center
DOI:
https://doi.org/10.12873/454mauricioKeywords:
Tuberculosis, Anemia, Estado Nutricional, Peso Corporal, Hemoglobina, TerapiaAbstract
Introduction: Tuberculosis is a major public health prob
lem in Peru, with nutritional repercussions that influence clinical outcomes. Weight loss and decreased hemoglobin are factors that can affect treatment response.
Objective: To evaluate the relationship between percent
age changes in body weight and hemoglobin levels in patients with tuberculosis treated at the Max Arias Schreiber Health Center, La Victoria, in 2025.
Methodology: Non-experimental, cross-sectional, correla
tional research. The medical records of 60 adult patients with a confirmed diagnosis of tuberculosis, treated between January 2022 and December 2024, with at least three months of treatment and complete data for analysis, were reviewed. Hemoglobin was obtained from the medical records, and weight changes were calculated using the formula: [(final weight − initial weight) / initial weight × 100]. Data normality was verified, and the Pearson correlation test was applied.
Results: Women showed an average weight change of
−1.0 ± 4.8% (range: −10.58% to 10%), while men showed
a weight gain of 0.71 ± 5.84% (range: −17.80% to 10.4%).
Initially, 53.3% had normal hemoglobin, 25.0% had mild anemia, and 21.7% had moderate anemia; no cases of severe anemia were identified. A weak positive correlation was found between weight change and hemoglobin levels (OR = 0.269; p = 0.038).
Conclusion: Body weight change is directly related to he
moglobin levels. Greater weight gain during treatment is associated with higher hemoglobin levels in patients with tuberculosis, highlighting the importance of nutritional monitoring in this population.
References
1. CDCespanol. Tuberculosis (TB). Acerca de la tuberculosis [Internet]. 2025 [citado 2025 Abr 20]. Disponible en: https://www.cdc.gov/tb/es/about/la-tuberculosis.html
2. Organización Mundial de la Salud. Global Tuberculosis Report 2024 [Internet]. 2024 [citado 2025 Abr 13]. Disponible en: https://www.who.int/teams/global-programme-on-tuberculosis-and-lung-health/tb-reports/global-tuberculosis-report-2024
3. Organización Mundial de la Salud. La tuberculosis resurge como principal causa de muerte por enfermedad infecciosa [Internet]. 2024 Oct 29 [citado 2025 Feb 18]. Disponible en: https://www.who.int/es/news/item/29-10-2024-tuberculosis-resurges-as-top-infectious-disease-killer
4. Organización Panamericana de la Salud. Situación de la Tuberculosis en las Américas [Internet]. 2024 [citado 2025 Abr 13]. Disponible en: https://www.paho.org/es/temas/tuberculosis/situacion-tuberculosis-americas
5. Centro Nacional de Alimentación y Nutrición (CENAN). Boletines epidemiológicos [Internet]. CDC MINSA; 2024 [citado 2025 Feb 18]. Disponible en: https://www.dge.gob.pe/portalnuevo/publicaciones/boletines-epidemiologicos/
6. Yang Q, Han J, Shen J, Peng X, Zhou L, Yin X. Diagnosis and treatment of tuberculosis in adults with HIV. Medicine (Baltimore). 2022 Sep 2;101(35):e30405. doi: 10.1097/MD.0000000000030405 DOI: https://doi.org/10.1097/MD.0000000000030405
7. Claramonte M, Peréz L, Noguera N. Desnutrición hospitalaria y variables antropométricas para la valoración nutricional. ResearchGate [Internet]. 2024 Dic 9 [citado 2025 Feb 18]. Disponible en: https://www.researchgate.net/publication/356786896_Desnutricion_hospitalaria_y_variables_antropometricas_para_la_valoracion_nutricional doi: 10.54139/salus.v25i2.60 DOI: https://doi.org/10.54139/salus.v25i2.60
8. Organización Mundial de la Salud. Weight Loss Management - OMS Urgent Care [Internet]. 2020 [citado 2025 Abr 15]. Disponible en: https://oms-urgentcare.com/services/weight-loss-management/
9. Manzini JL. Declaración de helsinki: Principios éticos para la in-vestigación médica sobre sujetos humanos. Acta bioethica.2000;6(2):321-34. DOI: https://doi.org/10.4067/S1726-569X2000000200010
10. Kalva J, Babu SP, Narasimhan PB, Raghupathy K, Ezhumalai K, Knudsen S, et al. Predictors of weight loss during the intensive phase of tuberculosis treatment in patients with drug-susceptible pulmonary tuberculosis in South India. J Public Health (Oxf). 2023 Aug 28;45(3):545-52. doi: 10.1093/pubmed/fdac141 DOI: https://doi.org/10.1093/pubmed/fdac141
11. Leon J, Sarkar S, Basu D, Nanda N, Joseph NM. Predictors of change in the anemia status among pulmonary tuberculosis patients following anti-tuberculosis treatment in Puducherry, India. Cureus. 2023 Sep;15(9):e44821. doi: 10.7759/cureus.44821 DOI: https://doi.org/10.7759/cureus.44821
12. Wagnew F, Alene KA, Kelly M, Gray D. Impacts of body weight change on treatment outcomes in patients with multidrug-resistant tuberculosis in Northwest Ethiopia. Sci Rep. 2024 Jan 4;14(1):508. doi: 10.1038/s41598-023-51026-y DOI: https://doi.org/10.1038/s41598-023-51026-y
13. Araújo-Pereira M, Krishnan S, Salgame P, Manabe YC, Hosseinipour MC, Bisson G, et al. Effect of the relationship between anaemia and systemic inflammation on the risk of incident tuberculosis and death in people with advanced HIV: a sub-analysis of the REMEMBER trial. EClinicalMedicine. 2023 Jun;60:102030. doi: 10.1016/j.eclinm.2023.102030 DOI: https://doi.org/10.1016/j.eclinm.2023.102030
14. Araújo-Pereira M, Nogueira BMF, Spener-Gomes R, Carvalho ACC, Sant’Anna FM, Figueiredo MC, et al. Anemia and anti-tuberculosis treatment outcome in persons with pulmonary tuberculosis: a multi-center prospective cohort study. J Infect Public Health. 2023 Jun;16(6):974-80. doi: 10.1016/j.jiph.2023.04.009 DOI: https://doi.org/10.1016/j.jiph.2023.04.009
15. Chen W, Ding Q, Zhang SK, Tong ZW, Ren F, Hu CM, et al. Nutritional status in patients with active pulmonary tuberculosis and new nutritional risk screening model for active tuberculosis: a national, multicenter, cross-sectional study in China. J Thorac Dis. 2023 May 30;15(5):2779-99. doi: 10.21037/jtd-23-623 DOI: https://doi.org/10.21037/jtd-23-623
16. Hitaish R, Maradi R, Umakanth S. Impact of anemia on sputum smear conversion and treatment outcomes among newly diagnosed tuberculosis patients in Southern India [Internet]. 2023 [citado 2025 Feb 18]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/37338470/ doi: 10.4103/ijmy.ijmy_24_23 DOI: https://doi.org/10.4103/ijmy.ijmy_24_23
Downloads
Published
License
Copyright (c) 2025 Nutrición Clínica y Dietética Hospitalaria
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Los lectores pueden utilizar los textos publicados de acuerdo con la definición BOAI (Budapest Open Access Initiative)
How to Cite
